Research Center for Mind, Brain & Learning

Journal Publications

• Liao W*;Lee KZ, 2023.09, 'CDKL5-mediated developmental tuning of neuronal excitability and concomitant regulation of transcriptome, ' Human Molecular Genetics, Vol.32, No.23, pp.3276-3298.(SCI)(*為通訊作者) Ref.
• Liang SL*;Liao W;Chen RS, 2023.03, 'Perinatal blockade of neuronal glutamine transport sex-differentially alters glutamatergic synaptic transmission and organization of neurons in the ventrolateral ventral media hypothalamus of adult rats, ' Journal of Neuroendocrinology, Vol.35, No.4, pp.e13253.(SCI)(*為通訊作者) Ref.
• Jhang CL;Lee HY;Chen JC;Liao W*, 2020.06, 'Dopaminergic loss of cyclin-dependent kinase-like 5 recapitulates methylphenidate-remediable hyperlocomotion in mouse model of CDKL5 deficiency disorder, ' Human Molecular Genetics, Vol.29, No.14, pp.2408-2419.(SCI)(*為通訊作者) Ref.
• Liao W*;Lee KZ;Su SH;Luo Y, 2020.03, 'Deficiency of cyclin-dependent kinase-like 5 causes spontaneous epileptic seizures in neonatal mice, ' bioRxiv, Vol.2020, No.3, pp.1-37.(*為通訊作者) Ref.
• Liao W*, 2019.01, 'Psychomotor dysfunction in Rett syndrome: insights into the neurochemical and circuit roots, ' Developmental Neurobiology, Vol.79, No.1, pp.51-59.(SCI)(*為通訊作者) Ref.
• Lee KZ*;Liao W, 2018.01, 'Loss of CDKL5 disrupts respiratory function in mice, ' Respiratory Physiology & Neurobiology, Vol.248, pp.48-54.(SCI)(*為通訊作者) Ref.
• Jhang CL;Huang TN;Hsueh YP;Liao W*, 2017.07, 'Mice lacking cyclin-dependent kinase-like 5 manifest autistic and ADHD-like behaviors, ' Human Molecular Genetics, Vol.26, No.20, pp.3922-3934.(SCI)(*為通訊作者) Ref.
• Su SH;Kao FC;Huang YB;Liao W*, 2015.04, 'MeCP2 in the rostral striatum maintains local dopamine content critical for psychomotor control, ' The Journal of Neuroscience, Vol.35, No.15, pp.6209-6220.(SCI)(*為通訊作者) Ref.
• Kao FC;Su SH;Carlson GC;Liao W*, 2015.01, 'MeCP2-mediated alterations of striatal features accompany psychomotor deficits in a mouse model of Rett syndrome., ' Brain Structure and Function, Vol.220, No.0, pp.419-434.(SCI)(*為通訊作者) Ref.
• Liao WL;Gandal MJ;Ehrlichman RS;Siegel SJ;Carlson GC*, 2012.04, 'MeCP2+/- mouse model of RTT reproduces auditory phenotypes associated with Rett syndrome and replicate select EEG endophenotypes of autism spectrum disorder, ' Neurobiology of Disease, Vol.46, No.1, pp.88-92.(SCI)(*為通訊作者) Ref.
• Liao WL;...;Liu FC*, 2008.04, 'Modular patterning of structure and function of the striatum by retinoid receptor signaling., ' Proc Natl Acad Sci USA, Vol.105, No.18, pp.6765-6770.(SCI)(*為通訊作者) Ref.
• Liao WL;...;Liu FC*, 2005, 'Retinoid signaling competence and RARbeta-mediated gene regulation in the developing mammalian telencephalon., ' Developmental Dynamics, Vol.232, pp.887-900.(SCI)(*為通訊作者) Ref.
• Liao WL;Liu FC*, 2005, 'RARbeta isoform-specific regulation of DARPP-32 gene expression: An ectopic expression study in the developing telencephalon, ' European Journal of Neuroscience, Vol.21, pp.3262-3268.(SCI)(*為通訊作者) Ref.
• Liao WL;Tsai HC;Wu CY;Liu FC*, 2005, 'Differential expression of RARbeta isoforms in the mouse striatum during development: a gradient of RARbeta2 expression along the rostrocaudal axis, ' Developmental Dynamics, Vol.233, pp.584-594.(SCI)(*為通訊作者) Ref.
• Lee YC;...;Liao WL;...;Chern Y*, 2003, 'Characterization of the rat A2a adenosine receptor gene: a 4.8-kb promoter-proximal DNA fragment confers selective expression in the central nervous system., ' European Journal of Neuroscience, Vol.18, No.7, pp.1786-1796.(SCI)(*為通訊作者) Ref.
• Liang KC*;Hon W;Tyan YM;Liao WL, 1994.12, 'Involvement of hippocampal NMDA and AMPA receptors in acquisition, formation and retrieval of spatial memory in the Morris water maze., ' The Chinese Journal of Physiology, Vol.37, No.4, pp.201-212.(SCI)(*為通訊作者) Ref.

Presentation/Proceedings

• Liao W*;Lee KZ, 2023.11, 'Developmental tuning of neuronal excitability and concomitant regulation of transcriptome by cyclin-dependent kinase-like 5, ' Neuroscience 2023, Society for Neuroscience.(*為通訊作者) Ref.
• Liao W*, 2023.09, 'CDKL5-mediated developmental tuning of neuronal excitability and concomitant regulation of transcriptome, ' 2nd Asia CDKL5 Workshop, For the advancement of understanding and treatment of CDKL5 deficiency disorder., IRCN - The University of Tokyo (Invited speaker), pp.22.(*為通訊作者) Ref.
• Liao W*, 2022.09, 'Deciphering age-dependent neuronal hyperexcitability caused by CDKL5 deficiency, ' TSfN2022 Program Book, Taiwan Neuroscience Alliance, pp.190.(*為通訊作者) Ref.
• Liao W*;Luo Y;Jhang CL, 2019.10, 'Methylphenidate ameliorates hyperlocomotion in CDKL5 deficient mice, ' The 49th Annual Meeting of Society for Neuroscience, The Society for Neuroscience.(*為通訊作者)
• Liao W*, 2019.09, 'Dissecting psychomotor dysfunction in mouse models of CDKL5 deficiency disorder, ' For the Advancement of Understanding and treating CDKL5 deficiency disorder., CDKL5 Workshop in Asia. The University of Tokyo (Invited speaker).(*為通訊作者) Ref.
• Luo Y;Liao W*, 2019.03, 'Aberrant protein phosphorylation of dopamine signaling molecules in mouse model of CDKL5 deficiency disorder, ' The 34th Joint Annual Conference of Biomedical Science, The Chinese Physiological Society.(*為通訊作者) Ref.
• Liao WL*;Jhang CL, 2017.11, 'Mice lacking cyclin-dependent kinase-like 5 manifest autistic and ADHD-like behaviors, ' Neuroscience 2017, Society for Neuroscience.(*為通訊作者) Ref.
• Liao W*;Jhang CL, 2016.11, 'Loss of cyclin-dependent kinase-­like 5 disrupts dopamine synthesis leading to comorbid autism-­ and ADHD-­like behaviors, ' Cell Symposium: Big Question in Neuroscience, Elsevier.(*為通訊作者)
• Liao W*, 2016.09, 'Local striatal dopamine governs psychomotor behavior in mice, ' Dopamine 2016, University of Vienna.(*為通訊作者)
• Liao WL*;Kao FC;Huang YB, 2014.11, 'Loss of MeCP2 in forebrain GABAergic neurons modulates striatal dopamine synthesis in a region-specific and non-cell autonomous manner, ' Neuroscience 2014, Society of Neuroscience (SfN).(*為通訊作者)
• Liao W*, 2014.08, 'Striatal MeCP2 maintains local dopamine content critical for psychomotor control in mouse models of Rett syndrome, ' Proceedings of the 12th Biennial Meeting of the Asian-Pacific Society for Neurochemistry, Journal of Neurochemistry, 130(Suppl.), Asian-Pacific Society for Neurochemistry/ Taiwan Neuroscience Society, pp.10.(SCI)(*為通訊作者)
• Liao WL*;Kao FC;Huang YB, 2014.07, 'MeCP2 in rostral forebrain is required for locomotion in mice., ' 9th FENS Forum of Neuroscience, Federal European Neuroscience Society (FENS).(*為通訊作者)
• Kao FC;Huang YB;Su SH;Liao WL*, 2013.10, 'Striatal MeCP2 is required for psychomotor control in mice, ' "Development, Function and Disease of Neural Circuits" at 2013 Cold Spring Harbor Asia Conference, Cold Spring Harbor Asia.(*為通訊作者)
• Huang YB;Kao FC;Liao WL*, 2013.03, 'Ultrasonic vocalization from separated pups in mouse models of Rett syndrome, ' The 28th Joint Annual Conference of Biomedical Science (JACBS), The Chinese Physiological Society (and other Societies), pp.P797.(*為通訊作者)
• Fang-Chi Kao;Wenlin Liao*, 2012.11, 'Loss of CDKL5 disrupts dopamine distribution in the striatum and causes autism-like behaviors in mice, ' Neural Circuit Basis of Behavior and its Disorders/ Abstracts of papers presented at the 2012 Cold Spring Harbor Asia Conference, Cold Spring Harbor Asia, pp.21.(*為通訊作者)
• Liao WL*;Kao FC, 2012, 'Loss of MeCP2 in GABAergic neurons disrupts the striatal properties leading to motor deficits of Rett Syndrome, ' The 42nd Annual Meeting of Society for Neuroscience, Society for Neuroscience (SfN).(SCI)(*為通訊作者)
• Liao WL*;Su SH;, 2011, 'Understanding the neural basis of motor deficits in a mouse model of Rett Syndrome, ' The 8th IBRO World Congress of Neuroscience;, International Brain Research Organization (IBRO).(SCI)(*為通訊作者)
• Su SH;Kao FC;Liao WL*, 2011, 'MeCP2 in GABAergic neurons is critical for normal locomotion, motor skill learning and striatal gene expression., ' Cell Symposia: Autism Spectrum Disorders: From Mechanisms to Therapies., Elsevier.(SCI)(*為通訊作者)
• Carlson GC*;Liao WL;, 2010, 'Hippocampal circuit disorder in mouse model of RTT is coincident with overt RTT-like symptoms: Potential model of developmental regression, ' The 40th Annual Meeting Society for Neuroscience;, Society for Neuroscience (SfN).(SCI)(*為通訊作者)
• Liao WL;Carlson GC*, 2009, 'Aberrant striatal gene expression and psychomotor impairments in a mouse model of Rett Syndrome, ' The 39th Annual Meeting, Society for Neuroscience.(SCI)(*為通訊作者) Ref.
• Liu FC*;Liao WL;Chambon P, 2009, 'Aberrant neurochemical expression in striosomal compartments of the striatum in RXRγ null mutant mice, ' The 39th Annual Meeting, Society for Neuroscience.(SCI)(*為通訊作者) Ref.
• Liao WL;Gandal MJ;Ehrlichman RS;Siegel SJ;Carlson GC*, 2009, 'Auditory evoked event related potentials and in vitro evoked circuit activity from adult MeCP2+/‐ mice indicate a shared autism phenotype and disrupted inhibitory cortical circuitry, ' The 39th Annual Meeting, Society for Neuroscience.(SCI)(*為通訊作者) Ref.
• Liao WL;Halene TB;Ehrlichman RS;Siegel SJ;Carlson GC*, 2008, 'Auditory evoked potentials in mice heterozygote for null-Mecp2 mutation., ' Program No. 447.10, The 38th Annual Meeting, Society for Neuroscience.(SCI)(*為通訊作者)
• Liao WL;Nguyen T;Carlson GC*, 2008, 'Impaired rotarod performance in Mecp2 deficient mice: Distinct behavioral patterns in truncated mutants and heterozygous null mice., ' The 9th Annual Meeting, International Rett Symdrome Foundation.(SCI)(*為通訊作者)
• Liu FC*;Liao WL;Chambon P, 2008, 'Modular patterning of structure and function of the striatum in the forebrain by retinoid receptor signaling., ' Program No. 426, The 67th Annual Meeting, Society for Developmental Biology.(SCI)(*為通訊作者)
• Liao WL;Chang JC;Tsai HC;Liu FC*, 2006, 'Regulation of cell proliferation of striatal progenitors by retinoic acid signaling., ' Program No. 27.19, The 36th Annual Meeting, Society for Neuroscience.(SCI)(*為通訊作者)
• Liao WL;Tsai HC;Wu CY;Liu FC*, 2004, 'Differential expression of RARbeta isoforms in the mouse striatum during development: a gradient of RARbeta2 expression along the rostrocaudal axis., ' Program No. 608.9, The 34th Annual Meeting, Society for Neuroscience.(SCI)(*為通訊作者) Ref.
• Liao WL;Tsai HC;Chambon P;Liu FC*, 2003, 'Retinoic acid receptor-mediated genetic control of pattern formation in the striatum of mammalian telencephalon., ' Program No. 560.7, The 33th Annual Meeting, Society for Neuroscience.(SCI)(*為通訊作者)
• Liao WL;Liu FC*, 2002, 'Up-regulation of dopamine signaling molecules in the developing cerebral cortex by ectopic expression of retinoic acid receptor-beta1., ' Program No. 24.15, The 32nd Annual Meeting, Society for Neuroscience.(SCI)(*為通訊作者)
• Liao WL;Liu FC*, 2000, 'Differential regulation of retinoid activity in different regions of the developing forebrain., ' Program No. 22.7, The 30th Annual Meeting, Society for Neuroscience.(SCI)(*為通訊作者)
• Liang KC*;Liao WL, 1995, 'Pretest infusion of lidocaine into the insular or medial prefrontal cortex impairs retrieval of remote memory in the inhibitory avoidance task., ' The 25th Annual Meeting, Society for Neuroscience, pp.1448.(SCI)(*為通訊作者)

Current Position

• Title
• Department
• Duration

• 教授
• 神經科學研究所
• 2021/02/01 ~ 2026/08/01